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Comments on: ARTS: Celebrate 100 years of insulin with the Thomas Fisher Rare Book Library (Mar. 2021) https://gleanernews.ca/arts-celebrate-100-with-the-thomas-fisher-rare-book-library-mar-2021/ Serving Toronto's most liveable community with the Annex Gleaner Fri, 02 Apr 2021 15:14:50 +0000 hourly 1 https://wordpress.org/?v=7.0.4 By: Dr. Arthur E. Zimerman https://gleanernews.ca/arts-celebrate-100-with-the-thomas-fisher-rare-book-library-mar-2021/comment-page-1/#comment-24964 Fri, 02 Apr 2021 15:14:50 +0000 http://gleanernews.ca/?p=9162#comment-24964 Dear Ms. Deen:
One problem, as other researchers got closer to discovering that a peptide hormone was involved in treating diabetes, was they made a proper acid-ethanol extraction of pancreas, but they boiled it for sterilzing. The boiling destroyed the peptide hormone, and that threw them off track, because they were still thinkng that a toxin caused diabetes.
In my Ph.D. thesis at U of T, 1973, I did a thorough review of the expriments leading up to Banting’s breakthrough idea that finally proved that a protein hormone was the key. Worth telling that prelinminary part of the story, before anyone understood anything about protein or peptide homones.

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